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Real members of MyMigraineTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Anyone Take Sumatriptan But Is Also On An Antidepressant?

A MyMigraineTeam Member asked a question 💭
Clayton, CA

Sumatriptan helps my migraines but I also take 20mg of Lexapro daily. There is a potential for drug interacton. My psychiatrist said he has never had a patient with an interaction but I just worry and that can make my migraines worse. Thank you!

January 18, 2018
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A MyMigraineTeam Member

I'm a pharmacist and also take 2 depression meds. I've never seen somebody have a problem with this interaction. That's not to say that no one has that interaction. I just know how many people are taking the type of antidepressant (SSRI) that you are (lots and lots) and have no problem taking migraine treatments like Sumatriptan. I wouldn't give it another thought, just enjoy the relief you get from your medications!

January 29, 2018
A MyMigraineTeam Member

Thank you so much for your answer, especially now because I have been having a few more migraines than I usually get.. I am tapering off 20mg of Lexapro and going back on 20mg of Paxil. Lexapro wasn't working for me and I had been on Paxil for years and it worked well for me. Thank you again 😊

January 29, 2018

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