Overview

Eprontia is approved by the U.S. Food and Drug Administration (FDA) for the preventive treatment of migraine in people 12 years of age and older. It is used to help reduce the frequency of migraine headaches in adolescents and adults who meet this age requirement. Eprontia is also known by its drug name, topiramate.

Eprontia is an anti-seizure drug. Scientists believe it works by calming overactive nerve signals in the brain and affecting certain brain chemicals that may trigger migraine attacks, helping to reduce how often migraines occur.

How do I take it?

Prescribing information states that Eprontia is taken by mouth as an oral solution. Treatment is typically started at a low daily dose and gradually increased over several weeks to a recommended maintenance dose for migraine prevention. It is usually taken once daily in the evening or divided into two daily doses. Eprontia should be taken exactly as prescribed by a healthcare provider.

Side effects

Common side effects of Eprontia include paresthesia (tingling sensations), anorexia (loss of appetite), weight loss, difficulty with memory, taste perversion (changes in taste), diarrhea, hypoesthesia (reduced sense of touch), nausea, abdominal pain, and upper respiratory tract infection.

Rare but serious side effects may include acute myopia (sudden nearsightedness) and secondary angle closure glaucoma (a serious eye condition that can cause permanent vision loss), visual field defects (loss of part of the field of vision), oligohidrosis (decreased sweating) and hyperthermia (elevated body temperature), metabolic acidosis (too much acid in the blood), suicidal behavior and ideation, cognitive or neuropsychiatric reactions (such as depression or mood problems), major congenital malformations (birth defects such as cleft lip and/or palate) and being small for gestational age if used during pregnancy, decreased bone mineral density (loss of bone strength), slowed growth in children, serious skin reactions including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), hyperammonemia (high ammonia levels in the blood) with or without encephalopathy (brain dysfunction), kidney stones, and hypothermia (low body temperature), especially when used with valproic acid.

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Label: Eprontia — Topiramate Solution — DailyMed