I have tried the ketamine infusion for my migraines and, for me, it made the migraine worse so I had them stop it. I have not had luck with any medications for my migraines including Botox, Aimovig, Emgality, currently on Vyepti with not much, if any, improvement, most of the triptans, Ubrelvy, many antidepressants, Topomax, gabapentin, Depakote, and I know I’m forgetting some others. I’m sorry I’m not much help to you. I hope you have better luck than I did with the ketamine and Vyepti.