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While before I could nap and get relief, now not even my prescribed rizatriptan is working. What has worked for you??

6 days ago
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A MyMigraineTeam Member

Ubelvy

20 hours ago
A MyMigraineTeam Member

Botox and Nurtec are the most effective. I also start off with Excedrin Migraine at the very beginning

3 days ago
A MyMigraineTeam Member

Are you able to use them for the same attack?

5 days ago
A MyMigraineTeam Member

I just recently started Rizatriptan and I found that and Ubrelvy were the only two things that actually worked on my intractable chronic migraines without aura. I’m also currently trying Botox

6 days ago
MyMigraineTeam

That sounds really exhausting, especially when something that used to help just... stops working. You're definitely not alone in this — many people with migraines find that their treatments need adjusting over time.

Since rizatriptan isn't cutting it anymore, here are some options worth discussing with your doctor: Try a Show Full Answer

That sounds really exhausting, especially when something that used to help just... stops working. You're definitely not alone in this — many people with migraines find that their treatments need adjusting over time.

Since rizatriptan isn't cutting it anymore, here are some options worth discussing with your doctor: Try a different triptan
Not all triptans work the same way in every person. For example, eletriptan is considered one of the strongest options, helping about 78% of people with chronic migraine. It may be worth asking your doctor about switching.

Change the form you're taking
Pills can be hard to absorb, especially if nausea is involved. Nasal sprays or injections work faster and skip the stomach entirely.

Combine medications
Pairing a triptan with an NSAID like ibuprofen or naproxen can sometimes provide better relief than either alone. Anti-nausea medications can also help your body absorb the triptan more effectively.

Ask about gepants
Newer medications like rimegepant (Nurtec ODT) or ubrogepant (Ubrelvy) work differently than triptans by blocking a protein linked to migraine pain — a good option if triptans aren't working.

See a migraine specialist
A neurologist can create a tailored treatment plan based on your specific symptoms, triggers, and history. One MyMigraineTeam member shared that keeping a headache journal helped them identify patterns and triggers, which allowed them to treat attacks earlier and get better relief — sometimes stopping a migraine before it fully hit.

Timing really matters too — triptans work best at the very first sign of an attack, not once it's in full swing. Don't give up; better relief is possible with the right adjustments! 💙

6 days ago

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