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A MyMigraineTeam Member asked a question 💭
Cypress, TX

I've been on Aimovig for 5 months now. Started taking the higher dose in January 2025. I take my Aimovig on the 22nd. It seems like every month, I get a 'breakthrough migraine' smack dab in the middle of the month. Is that normal?

March 10, 2025 (edited)
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Answer Summary

Members reassured someone experiencing monthly breakthrough migraines on Aimovig that this pattern is common, with many sharing that CGRP... Read more

Members reassured someone experiencing monthly breakthrough migraines on Aimovig that this pattern is common, with many sharing that CGRP medications significantly reduce migraine frequency and intensity even when they don't eliminate attacks entirely. Several members recommended staying on Aimovig longer since response times vary widely, with one member noting it took two full years to see meaningful results, while others suggested asking for a rescue medication like Nurtec or sumatriptan to manage breakthrough episodes rather than switching treatments too quickly. A recurring theme was the importance of communicating openly with your neurologist about breakthrough patterns, considering medication samples to test options before insurance battles, and recognizing that going from constant migraines to just a handful of days per month represents real progress worth building on.

A MyMigraineTeam Member

Ok since you have only been on it for a little while and it isn’t working as well as you’d like to I would tell your doctor then and see if he can put you on something else. Usually they like you to be on a medication for at least 3 months so that you give it enough time to work. Since you’ve been on it for 5 months now and it isn’t working as well as you’d want it too, ask dr to give you something else. No since in suffering when there are many other medications that can work for you without the break throughs.

Hugs
Rita J

March 11, 2025
A MyMigraineTeam Member

Ok, thanks for the info.

The month prior to me starting Aimovig, I had a migraine that lasted all the way through September 2024. I couldn't get a break from it. That's what prompted my neuro to put me on Aimovig. Since my neuro put me on the 140mg, I only have maybe 8-12 migraine days a month.

March 10, 2025 (edited)
A MyMigraineTeam Member

I have 1 or 2 migraines a month only lasting 2 to 3. The medication seems to wear off after 2 weeks. But, considering what an improvement this has made- it is a win.

March 12, 2025 (edited)
A MyMigraineTeam Member

No, Aimovig is the only anti-CGRP that I've tried. Before that, I was just on a synthetic anticonvulsant that was used as an off-label. Was on it from 2018 (year I was diagnosed with migraine) to January of this year. I usually update my doctor weekly about my seizures and migraine, anyway.

March 11, 2025
A MyMigraineTeam Member

Maybe talk to your neuro and let him/her know that you are still getting break through migraines. He/She may want to change it to something else. Have you ever tried Ajovy? It is an injectable it worked for a while but then stopped working. I’ve been through pretty much all the newer medications and old alike. I think my neuro has pretty much given up on me after 25 years…lol.

Hopefully you can get with your neuro so you can get rid of the breakthroughs quickly!

Hugs
Rita J

March 11, 2025

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