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A MyMigraineTeam Member asked a question 💭
Kingsport, TN
November 21, 2025
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A MyMigraineTeam Member

Have been using Ajovy 2021 and it's been working quite well. I have been going through severe chronic migraines every so often due to a surgery after effect that I need to work with. Between the Botox and Ajovy the migraines have been managable but having added Ubrelvy into the mix is a blessing.

I take Ajovy every 28 days and from what I can recall it was not until after the fourth injection that I began to notice a larger decrease to the migraine activity.

December 5, 2025
MyMigraineTeam

Are you wondering if other people use Ajovy and whether it's effective for preventing migraines?

Yes, Ajovy (fremanezumab-vfrm) is used by people with migraines to help prevent attacks. It's injected under the skin and can be given either monthly or every three months, depending on what works best for your treatment plan.

Show Full Answer

Are you wondering if other people use Ajovy and whether it's effective for preventing migraines?

Yes, Ajovy (fremanezumab-vfrm) is used by people with migraines to help prevent attacks. It's injected under the skin and can be given either monthly or every three months, depending on what works best for your treatment plan.

Studies have shown that Ajovy can reduce the frequency of migraine attacks, even in people who haven't had success with other treatments. Research found that people using Ajovy had an average reduction of four migraine days per month, compared to two days for those receiving a placebo.

Ajovy works by binding to CGRP, a protein involved in migraine attacks. It's particularly helpful for people who are looking for a preventive treatment option that doesn't require daily medication.

Keep in mind that migraine treatments work differently for everyone, so what helps one person significantly might have varying results for another. It's worth discussing with your doctor whether Ajovy might be a good fit for your specific situation.

November 21, 2025
A MyMigraineTeam Member

when I first tried Vyepti the administering nurse said it takes 3 times to be effective. That was BIG news to me, and had not heard that from the doc. If fact he was puzzled when I repeated the comment to him. It seems like I took it 4 times and still was not well, until I combined it with Xeomin (a form of Botox). Within two weeks of that, I was finally better.

Btw, my strong impression from the neuro is that Vyepti is the biggest gun to bring to the battle.

December 5, 2025
A MyMigraineTeam Member

Tried it no effect, tried Emgality about the same response just tried th iv form vyepti last week Dr says it takes a couple of weeks to see if helping, started at the low dose 100mg 🤞

November 22, 2025
A MyMigraineTeam Member

I used Ajovy in the past. It helped in the short term, but then nothing. I still get 4-5 migraines a week. I'm lucky if I go a day without a migraine.

November 22, 2025

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