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When multiple medications haven't worked, there are still several long-term management options worth exploring with your neurologist. The good news is that migraine treatment has advanced significantly, and there are both medication and non-medication approaches available.

Here's a breakdown of options that may be Show Full Answer

When multiple medications haven't worked, there are still several long-term management options worth exploring with your neurologist. The good news is that migraine treatment has advanced significantly, and there are both medication and non-medication approaches available.

Here's a breakdown of options that may be considered:

Newer Medication Options
- CGRP monoclonal antibodies (like Aimovig, Ajovy, Emgality, or Vyepti) — these are specifically designed for migraine prevention and have shown effectiveness even for people who haven't responded to older treatments
- CGRP receptor antagonists (like Nurtec ODT or Qulipta) — can be used for both prevention and acute relief

Non-Medication Approaches
- Botox injections — FDA-approved for chronic migraine prevention, given every 3 months
- Nerve block injections — such as sphenopalatine ganglion blocks, administered through the nose
- Migraine devices — a growing area with options that don't involve medication at all
- Infusion therapy — some MyMigraineTeam members have found regular infusions helpful It's also worth reviewing *how* current medications are being used. Overusing certain acute treatments can actually increase migraine frequency and make preventive treatments less effective over time.

A neurologist can help evaluate your full history and tailor a plan that considers your specific migraine type, symptoms, and any previous treatment responses. Don't hesitate to ask directly: "What newer options exist that I haven't tried yet?"

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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