Vivactil is a prescription drug approved by the Food and Drug Administration (FDA) to treat depression in people who are under close medical supervision. Vivactil is also known by its drug name, Protriptyline. Some antidepressants are prescribed off-label to prevent migraines.

Vivactil is a tricyclic antidepressant. Vivactil is believed to work by changing the balance of neurotransmitters in the brain.

How do I take it?
Vivactil is generally taken three or four times a day.

Vivactil comes in tablet form.

Side effects... read more

The FDA-approved label for Vivactil lists common side effects including headache, fatigue, ringing in the ears, weakness, drowsiness, dizziness, restlessness, insomnia, nightmares, nausea, vomiting, constipation, stomach pain, breast swelling in women, and sexual difficulties.

Rare but serious side effects listed for Vivactil include worsening depression, increased suicide risk, glaucoma, and increased heart rate (tachycardia).

For more details about this treatment, visit:
Vivactil – RxList

Migraine Treatment with Antidepressants: an introduction – Migraine.com

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